Journal: PLoS ONE
Article Title: A Signature of Maternal Anti-Fetal Rejection in Spontaneous Preterm Birth: Chronic Chorioamnionitis, Anti-Human Leukocyte Antigen Antibodies, and C4d
doi: 10.1371/journal.pone.0016806
Figure Lengend Snippet: (A) A representative case showing the presence of anti-HLA class I antibodies and the absence of anti-HLA class II antibodies in maternal serum with FlowPRA®-I and -II screening tests, followed by flow cytometry. (B) Spontaneous preterm birth cases have a higher maternal anti-HLA class I seropositivity than normal term birth cases (p<0.01). TB , normal term birth; sPTB , spontaneous preterm birth.
Article Snippet: Flow cytometric analysis of panel-reactive anti-HLA class I and class II antibodies in maternal and cord blood sera was performed using the FlowPRA®-I screening test (One Lambda Inc., Canoga Park, CA, USA) and FlowPRA®-II screening test (One Lambda Inc.) according to the manufacturer's instructions.
Techniques: Flow Cytometry